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</o:shapelayout></xml><![endif]--></head><body lang=EN-US link="#0563C1" vlink="#954F72"><div class=WordSection1><p class=MsoNormal style='margin-top:3.0pt'><b><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif'>Closing Date for Applications: </span></b><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif'>Midnight (UK time), May 12, 2019<o:p></o:p></span></p><p class=MsoHeader style='margin-top:3.0pt'><b><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif'>Line of Management: Senior Vice President QSP</span></b><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif'><o:p></o:p></span></p><p class=MsoNormal style='margin-top:3.0pt'><b><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif'>Position Type: </span></b><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif'>Full Time<b><o:p></o:p></b></span></p><p class=MsoNormal style='margin-top:3.0pt'><b><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif'>Salary and benefits:</span></b><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif'> Dependent on qualifications, experience and location</span><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif'><o:p></o:p></span></p><p class=MsoNormal style='margin-top:3.0pt'><b><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif'>Location:</span></b><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif'> QSP offices in Sheffield or Canterbury (United Kingdom).  Alternative locations and flexible working arrangements can be considered depending on individual circumstances.<i><span style='color:black'><o:p></o:p></span></i></span></p><p class=MsoNormal style='margin-top:12.0pt;background:white'><b><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-language:EN-GB'>Job Overview:<o:p></o:p></span></b></p><p class=MsoNormal style='text-align:justify'><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-language:EN-GB'>Certara is expanding its Quantitative Systems Pharmacology (QSP) services in Neurodegeneration and has bold ambitions to revolutionise drug discovery and development in this area of highest medical and societal need.  As a result, we have an immediate opening for a Computational Neuroscience Modeller to join our QSP group.  This is a unique opportunity to work in a multi-disciplinary team in a world-class organisation and utilise your advanced computational skills to make a difference to the lives of patients with neurodegenerative diseases.<o:p></o:p></span></p><p class=MsoNormal style='text-align:justify'><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-language:EN-GB'><o:p> </o:p></span></p><p class=MsoNormal style='text-align:justify'><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-language:EN-GB'>Successful applicants will contribute to the development of multi-scale QSP models for neurodegenerative diseases, such as Alzheimer’s and Parkinson’s disease.  Specifically, they will develop biophysically realistic neuronal circuit-level computer models, linking pathways, pharmacological effect and clinical outcomes.<o:p></o:p></span></p><p class=MsoNormal style='text-align:justify'><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-language:EN-GB'><o:p> </o:p></span></p><p class=MsoNormal style='text-align:justify'><b><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-language:EN-GB'><o:p> </o:p></span></b></p><p class=MsoNormal style='text-align:justify'><b><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-language:EN-GB'>Requirements</span></b><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-language:EN-GB'>:<o:p></o:p></span></p><p class=MsoNormal style='text-align:justify'><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-language:EN-GB'><o:p> </o:p></span></p><p class=MsoNormal style='text-align:justify'><b><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-language:EN-GB'>Essential <o:p></o:p></span></b></p><ul style='margin-top:0in' type=disc><li class=MsoNormal style='margin-left:38.3pt;text-align:justify;mso-list:l0 level1 lfo1'><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-language:EN-GB'>PhD and at least 2 years postdoctoral experience in computational biosciences<o:p></o:p></span></li><li class=MsoNormal style='margin-left:38.3pt;text-align:justify;mso-list:l0 level1 lfo1'><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif'>Strong publication record (commensurate with level of experience)<o:p></o:p></span></li><li class=MsoNormal style='margin-left:38.3pt;text-align:justify;mso-list:l0 level1 lfo1'><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-language:EN-GB'>Experience in computational neuroscience and neural modelling with NEURON or equivalent software<o:p></o:p></span></li><li class=MsoNormal style='margin-left:38.3pt;text-align:justify;mso-list:l0 level1 lfo1'><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-language:EN-GB'>Excellent programming skills<o:p></o:p></span></li><li class=MsoNormal style='margin-left:38.3pt;text-align:justify;mso-list:l0 level1 lfo1'><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-language:EN-GB'>Good written and oral communication skills<o:p></o:p></span></li><li class=MsoNormal style='margin-left:38.3pt;text-align:justify;mso-list:l0 level1 lfo1'><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif'>Combines scientific excellence with ability to make impact in drug discovery and development programs in a timely manner<o:p></o:p></span></li><li class=MsoNormal style='margin-left:38.3pt;text-align:justify;mso-list:l0 level1 lfo1'><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif'>Ability to work virtually with project teams across different locations and time zones<o:p></o:p></span></li></ul><p class=MsoNormal style='margin-left:74.3pt;text-align:justify'><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-language:EN-GB'><o:p> </o:p></span></p><p class=MsoNormal style='text-align:justify'><b><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-language:EN-GB'>Desirable<o:p></o:p></span></b></p><ul style='margin-top:0in' type=disc><li class=MsoNormal style='margin-left:38.3pt;text-align:justify;mso-list:l0 level1 lfo1'><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-language:EN-GB'>Experience in QSP modelling<b><o:p></o:p></b></span></li><li class=MsoNormal style='margin-left:38.3pt;text-align:justify;mso-list:l0 level1 lfo1'><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-language:EN-GB'>Experience in modelling neurodegenerative diseases<b><o:p></o:p></b></span></li><li class=MsoNormal style='margin-left:38.3pt;text-align:justify;mso-list:l0 level1 lfo1'><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-language:EN-GB'>Experience working in drug discovery and development<b><o:p></o:p></b></span></li></ul><p class=MsoNormal style='margin-top:12.0pt;background:white'><b><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-language:EN-GB'>Company Overview:</span></b><b><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif;mso-fareast-language:EN-GB'><o:p></o:p></span></b></p><p class=MsoNormal style='text-align:justify'><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif'>Certara is a world leader in bio-simulation which combines sophisticated research and development informatics with the power of predictive science methodologies to span the drug development spectrum and offer pharma a previously unavailable ‘end-to-end’ solution in the quest for improving human health.  The Certara UK division develops industry-standard mechanistic models and tools in the areas of physiologically-based pharmacokinetics (PBPK), quantitative systems pharmacology (QSP) and quantitative systems toxicology and safety (QSTS).<o:p></o:p></span></p><p class=MsoNormal style='text-align:justify'><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif'><o:p> </o:p></span></p><p class=MsoNormal style='text-align:justify'><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif'>Certara combines sophisticated research and development informatics with the power of predictive science methodologies to span the drug development spectrum and offer pharma a previously unavailable ‘end-to-end’ solution in the quest for improving human health.<o:p></o:p></span></p><p class=MsoNormal style='text-align:justify'><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif'><o:p> </o:p></span></p><p class=MsoNormal style='text-align:justify'><strong><span lang=EN-GB style='font-weight:normal'><o:p> </o:p></span></strong></p><p class=MsoNormal style='text-align:justify'><strong><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif'>Applications: </span></strong><b><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif'><br></span></b><span lang=EN-GB style='font-size:10.0pt;font-family:"Tahoma",sans-serif'>Please send your CV, covering letter and the names of two references to the Certara Careers Page: www.certara.com</span><span lang=EN-GB><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri",sans-serif'><o:p> </o:p></span></p></div></body></html>