[Comp-neuro] What is the precision of synaptic plasticity?

Terry Sejnowski terry at salk.edu
Thu Mar 12 04:44:13 CET 2015


Hippocampal Spine Head Sizes are Highly Precise

Thomas M Bartol, Cailey Bromer, Justin P Kinney, 
Michael A Chirillo, Jennifer N Bourne, Kristen M Harris, 
Terrence J Sejnowski

The size of an EPSP is highly correlated with the
the spine head volume for excitatory synapses
on pyramidal cells.  Spine heads on a dendrite 
originating from the same axon had the same volume,
regardless of whether they were large or small.
This has implications for the precision of the 
mechanisms underlying synaptic plasticity.



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