[Comp-neuro] RE: Post-Doctoral position at Blue Brain Project, EPFL, in Mesoscale Cortical Synthesis

james bower bower at uthscsa.edu
Thu Jul 4 16:24:23 CEST 2013

Why not, it's the summer, CNS meeting is coming up, and it has been a long time since our previous discussion of 'noise in the nervous system'.

So, why not:

Serious 	question:  do cortical columns actually exist? Is this the right way to think about cortical processing?

More formally, is the idea of a cortical column, originally proposed by Mountcastle in the 1950s as a "computational" (in current lexicon)  building block for cerebral cortex:

1) supported by the data

2) the right way to think about cortical structure?  computational or otherwise.

In case anyone is wondering, I think not - and have found it mildly amusing that this project is devoted to reconstructing something that probably doesn't exist.


Jim Bower

On Jul 4, 2013, at 7:43 AM, Shillcock Julian Charles <julian.shillcock at epfl.ch> wrote:

> The Blue Brain Project has modelling infrastructure for constructing in silico neocortical columns containing about 30,000 neurons, distributing the cells through the column and forming synapses. Several such columns have already been assembled into a planar hexagonal mosaic containing up to 1,000,000 neurons. However, axons grow long distances along tracts within the brain's white matter, and the next stage of development is to populate three-dimensional mesh models of brain regions with appropriately-shaped mesocircuits, adjusting their dimensions and shape to match rodent brain anatomy, and connecting the circuits according to known large-scale connectomics data,  yielding a complete rat brain model containing on the order of tens of millions of neurons.
> Please see this page for more deals: http://emploi.epfl.ch/page-94325-en.html
> Julian Shillcock
> _______________________________________________
> Comp-neuro mailing list
> Comp-neuro at neuroinf.org
> http://www.neuroinf.org/mailman/listinfo/comp-neuro



Dr. James M. Bower Ph.D.

Professor of Computational Neurobiology

Barshop Institute for Longevity and Aging Studies.

15355 Lambda Drive

University of Texas Health Science Center 

San Antonio, Texas  78245


Phone:  210 382 0553

Email: bower at uthscsa.edu

Web: http://www.bower-lab.org

twitter: superid101

linkedin: Jim Bower



The contents of this email and any attachments to it may be privileged or contain privileged and confidential information. This information is only for the viewing or use of the intended recipient. If you have received this e-mail in error or are not the intended recipient, you are hereby notified that any disclosure, copying, distribution or use of, or the taking of any action in reliance upon, any of the information contained in this e-mail, or

any of the attachments to this e-mail, is strictly prohibited and that this e-mail and all of the attachments to this e-mail, if any, must be

immediately returned to the sender or destroyed and, in either case, this e-mail and all attachments to this e-mail must be immediately deleted from your computer without making any copies hereof and any and all hard copies made must be destroyed. If you have received this e-mail in error, please notify the sender by e-mail immediately.


-------------- next part --------------
An HTML attachment was scrubbed...
URL: http://www.neuroinf.org/pipermail/comp-neuro/attachments/20130704/0da17e53/attachment.html

More information about the Comp-neuro mailing list