[Comp-neuro] PhD position in computational neuroscience (Goethe University Frankfurt)

Peter Jedlicka jedlicka at em.uni-frankfurt.de
Thu Jul 12 15:57:26 CEST 2012

Applications are invited for a 3-year PhD position to work with Dr.  
Peter Jedlicka at Goethe-University Frankfurt in an NSF & BMBF funded  
US-Germany project aimed at understanding how chloride dynamics affect  
cerebellar computation. This project is in collaboration with Dr.  
Fidel Santamaria at The University of Texas at San Antonio and Dr.  
Thomas Kuner at Heidelberg University. The PhD student will be  
involved in the generation and implementation of computational models  
focusing on chloride-dependent changes in cerebellar inhibition. The  
student will be using computer simulations to reproduce/predict data  
from electrophysiology experiments on neurons expressing diverse  
fluorescent molecules that report chloride concentrations. Visits to  
US for short-term and long-term periods of time to learn techniques  
and exchange information are part of the activities of this grant. The  
successful candidate should have a background in physics, mathematics,  
engineering or computational neuroscience. Experience in scientific  
programming is highly desirable. The appointment will be starting in  
November/December 2012.

Please submit a CV and statement of research interests to:

Dr. Peter Jedlicka (jedlicka at em.uni-frankfurt.de)
NeuroScience Center
Clinical Neuroanatomy (Anatomy I)
Theodor-Stern-Kai 7
60590 Frankfurt

The project is related to these recent publications:

Jedlicka P, Deller T, Gutkin BS, Backus KH (2011) Activity-dependent  
intracellular chloride accumulation and diffusion controls GABA(A)  
receptor-mediated synaptic transmission. Hippocampus 21:885-98.

Santamaria F, Wils S, De Schutter E, Augustine GJ (2011). The  
diffusional properties of dendrites depend on the density of dendritic  
spines. Eur. J. Neurosci. 34:561-8.

Coop AD, Cornelis H, and Santamaria F (2010). Dendritic excitability  
modulates dendritic information processing in a Purkinje cell model.  
Front. Comput. Neurosci. 4:6. doi:10.3389/fncom.2010.00006.

Santamaria F, Wils S, De Schutter E, Augustine GJ (2006). Anomalous  
diffusion in Purkinje cell dendrites caused by spines. Neuron  

Dübel J, Haverkamp S, Schleich W, Augustine GJ, Feng G, Kuner T, Euler  
T (2006). Two-photon imaging reveals somato-dendritic chloride  
gradient in retinal ON-type bipolar cells expressing the biosensor  
Clomeleon. Neuron 49, 81-49.

P.S. If you are interested and will be attending FENS 2012 in  
Barcelona just send me an email or give me a call so that we can meet  
and talk.

Peter Jedlicka, MD, PhD
NeuroScience Center
Clinical Neuroanatomy (Anatomy I)
Theodor-Stern-Kai 7
D-60590 Frankfurt am Main
Phone: ++49 (179) 238 6269
Fax:   ++49 (69) 6301 6425
Email: jedlicka at em.uni-frankfurt.de

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