[Comp-neuro] Postdoctoral Position - Morphologic Models of Neurons in Aging (Patrick Hof and Christina Weaver)

Christina M. Weaver christina.weaver at fandm.edu
Tue Dec 11 21:08:31 CET 2012

*Postdoctoral Position:  Morphologic Models of Neurons in Aging*

***  Second announcement – submit by December 15, 2012 for full
consideration ***

The laboratories of Dr. Patrick Hof  (Department of Neuroscience, Mount
Sinai School of Medicine, New York, NY) and Dr. Christina Weaver
(Department of Mathematics, Franklin & Marshall College, Lancaster, PA)
seek a highly motivated postdoctoral fellow to develop computational models
of cortical pyramidal neurons, and new methods to analyze these models.  The
NIH funded research explores interactions between morphological and
physiological changes in the aging primate cortex.  The postdoctoral fellow
will be based at Mount Sinai’s Department of Neuroscience and Computational
Neurobiology and Imaging Center (CNIC) with Dr. Hof, but will collaborate
closely with Dr. Weaver and with Dr. Jennifer Luebke (Boston University
School of Medicine, Boston, MA).  The candidate will also have the
opportunity to learn experimental techniques including confocal imaging and
in vitro electrophysiology.  Further information on the Computational
Neurobiology and Imaging Center can be found at http://www.mssm.edu/cnic .

Relevant publications include

Amatrudo JM, *Weaver* CM, Crimins JL, Hof PR, Rosene DL, *Luebke* JI.
of highly distinctive structural properties on the excitability of
pyramidal neurons in monkey visual and prefrontal
cortices.<http://www.ncbi.nlm.nih.gov/pubmed/23035077>J Neurosci.
32(40):13644-60, (2012).

Yadav A, Gao YZ, Rodriguez A, Dickstein DL, Wearne SL, *Luebke* JI, Hof PR,
*Weaver* CM.  Morphologic evidence for spatially clustered spines in apical
dendrites of monkey neocortical pyramidal
J Comp Neurol. 520(13):2888-902, (2012).

*Luebke* JI, *Weaver* CM, Rocher AB, Rodriguez A, Crimins JL, Dickstein DL,
Wearne SL, Hof PR.  Dendritic vulnerability in neurodegenerative disease:
insights from analyses of cortical pyramidal neurons in transgenic mouse
models. <http://www.ncbi.nlm.nih.gov/pubmed/20177698>  Brain Struct Funct.
214(2-3):181-99, (2012).

Weaver CM, Wearne SL.  Neuronal firing sensitivity to morphologic and
active membrane parameters. <http://www.ncbi.nlm.nih.gov/pubmed/18208320>  PLoS
Comput Biol. 4(1):e11, (2008).

Candidates should have, or be near finishing, a Ph.D. in math, physics or
computer science with a strong demonstrated interest in neuroscience, or a
Ph.D. in neuroscience with a strong computational background.  Experience
with computer programming is essential.  Experience with NEURON
compartmental modeling software and automated parameter optimization is
preferred.  Strong communication skills in English are required.  The
position is available immediately, for an initial two-year appointment
(renewable). Salary will be commensurate with experience, according to the
NIH NRSA pay scale.

Application review will begin on December 15, 2012, and will continue until
the position is filled.  Interested applicants should send their CV, a
brief statement of current and future research interests, and the contact
information of three references to christina.weaver at fandm.edu.
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