[Comp-neuro] Post-doctoral position at Boston University,
Center for Memory and Brain
hasselmo at bu.edu
Wed Feb 25 18:19:12 CET 2009
POST-DOCTORAL FELLOWSHIP -
CENTER FOR MEMORY AND BRAIN, BOSTON UNIVERSITY
A full-time postdoctoral position is available in the Center for Memory
and Brain, Department of Psychology and Program in Neuroscience at Boston
The post-doctoral fellow will develop compartmental biophysical
simulations of entorhinal, subicular and hippocampal neurons and circuits
involved in encoding and retrieval of sequences for memory guided
behavior. The post-doctoral fellow will join a large community of
researchers in the Center for Memory and Brain.
Research will focus initially on developing compartmental biophysical
simulations of grid cell responses in entorhinal cortex, based on cellular
mechanisms such as membrane potential oscillations and persistent spiking
(Giocomo et al., 2007; Hasselmo, 2008a). Simulations will use standard
packages such as MATLAB, Neuron and GENESIS.
Modeling will include interaction with experimental work using whole-cell
patch recording in slice preparations of entorhinal cortex and subiculum
(Giocomo and Hasselmo, 2008; Yoshida et al., 2008) and experimental work
on unit recording data in awake, behaving rats (Lee et al., 2006;
Hasselmo, 2008b). Collaborations will include Dr. Erik Fransen at the
Royal Institute of Technology in Stockholm, Sweden, and Prof. Howard
Eichenbaum and Prof. Chantal Stern in the Center for Memory and Brain at
Boston University. Simulations will use standard packages such as MATLAB,
Neuron or GENESIS.
Candidates should have previous experience with developing compartmental
biophysical simulations of neurons. E-mail your CV and the e-mail
addresses of two references to Prof. Michael Hasselmo, hasselmo at bu.edu.
Boston University is an Affirmative Action, Equal Opportunity Employer.
Citations: (PDF files available at
Giocomo LM, Zilli EA, Fransen E, Hasselmo ME. (2007) Temporal frequency of
subthreshold oscillations scales with entorhinal grid cell field spacing.
Giocomo, L.M., Hasselmo, M.E. (2008) Time constant of I(h) differs along
dorsal to ventral axis of medial entorhinal cortex. Journal of
Hasselmo, M.E. (2008a) Grid cell mechanisms and function: Contributions of
entorhinal persistent spiking and phase resetting. Hippocampus 18:
Hasselmo, M.E. (2008b) Temporally structured replay of neural activity in
a model of entorhinal cortex, hippocampus and postsubiculum. Eur. J.
Lee I., Griffin A., Zilli E., Eichenbaum H., Hasselmo M.E. (2006) Gradual
translocation of spatial correlates of neuronal firing in the hippocampus
toward prospective reward locations. Neuron 51:639-50.
Yoshida, M., Fransen, E., Hasselmo, M.E. (2008) mGluR-dependent persistent
firing in entorhinal cortex layer III neurons. Eur. J. Neurosci.
Prof. Michael Hasselmo
Center for Memory and Brain
Department of Psychology and
Program in Neuroscience
2 Cummington St.,
Boston, MA, 02215, USA
Tel: (617) 353-1397,
e-mail: hasselmo at bu.edu
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