[Comp-neuro] Postdoctoral Position in computational neuroscience of nicotine-dopamine interactions

Boris.Gutkin boris.gutkin at ens.fr
Thu Apr 23 11:42:06 CEST 2009

A postdoctoral position is available in the Group for Neural Theory
(http://www.gnt.ens.fr/), at the ENS in Paris/France to develop
computational models of nicotine addiction in the brain. The candidate
will participate in a project in which the interaction between nicotine
and dopamine pathways are studied on the level of receptor dynamics and
microcircuit behavior in the ventral tegmental area (VTA). Initial
research directions include: 1. to construct spiking network models of
the VTA  in order to understand how addictive drugs, and nicotine
specifically, usurp the normal function of the dopaminergic signalling
by controlling the activity modes of the neurons; 2. to integrate the
VTA circuit in the mesocorticolimbic feedback loop model. The  
candidate will have the opportunity to develop further directions  
together with the project leaders and collaborators. This work is
carried out in close interaction with experimental labs in the
Paris region and abroad.

The ideal candidate will have a doctoral degree, or equivalent, with an
emphasis on computational approaches to the biology of neuronal systems.
Basic knowledge of neuronal signal integration and signal transmission
in spiking neuronal networks is required. Programming in Matlab and
C/C++ will be part of the project.

The position is funded until 01/2011 with possible extensions. Salary is
commensurate with experience and the position carries a full social
security and health coverage. Generous travel allowances will be  

Dr. Boris S Gutkin
Senior Research Scientist
Group for Neural Theory
29 rue d'Ulm
75005 Paris
tel: +33 (0)1 44 32 29 56
fax: +33 (0)

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