[Comp-neuro] Postdoctoral Research Fellow/Assistant in Computational
Neuroscience, University of Plymouth, UK
R.Borisyuk at plymouth.ac.uk
Tue Apr 7 21:15:25 CEST 2009
University of Plymouth, UK
Centre for Theoretical and Computational Neuroscience
A postdoctoral Research Fellow/Assistant is required for a 3 year project in the Research Group of Prof Roman Borisyuk, Centre for Theoretical and Computational Neuroscience at the University of Plymouth, UK (http://www.research.plymouth.ac.uk/ctcn/ ).
This BBSRC funded collaborative project (with the University of Bristol) will investigate whether simple developmental rules allow neuronal circuits in the early vertebrate nervous system to self-assemble and control motor behaviour. Recent work on the young Xenopus tadpole has defined the features, connections and activity patterns of the major neuron groups controlling both swimming and struggling locomotion. This knowledge offers a unique opportunity in a vertebrate to investigate and model the development of defined neuronal networks.
The Research Fellow will develop a first biologically realistic computational model of the tadpole nervous system which will demonstrate swimming and struggling locomotion. This model will include both anatomy and electrophysiology of neuronal circuitry relevant to tadpole behaviour. Model development will include mathematical formulation, design of numerical algorithms and software, model simulation, analysing and reporting simulation results, discussion of results and model adjustment etc. with biological partners in Bristol. Visualization of the simulation results and programming a virtual tadpole will be a part of the workload.
Project work will involve interaction with two other postdocs in the Xenopus Neurobiology Research Group of Prof Alan Roberts and Dr Steve Soffe at the University of Bristol (http://www.bio.bris.ac.uk/research/neuro/xgroup.htm).
The appointed person should have education at PhD level in computer science, mathematics or similar disciplines, experience in computational neuroscience, mathematical and computational modelling, a strong background in software engineering and excellent programming skills. Experience in software development and visualization techniques will be a great advantage.
This position is available for up to 3 years from May 2009 or as soon as possible thereafter. Salary is dependent on experience but will be in the range of £30,594 - to £32,458.
Informal enquiries are also welcome via e-mail (rborisyuk at plymouth.ac.uk<mailto:rborisyuk at plymouth.ac.uk>)
Applications should be made to the University of Plymouth before the closing date of 24th of April 2009
Recent publications relevant to the project:
Borisyuk R., Cooke T., Roberts A. (2008) Stochasticity and functionality of neural systems: Mathematical modelling of axon growth in the spinal cord of tadpole. BioSystems, 93:101-114
Li W.-C., Cooke T., Sautois B., Soffe S., Borisyuk R. and Roberts A. (2007) Axon and dendrite geography predict the specificity of synaptic connections in a functioning spinal cord network. Neural Development, 2:17
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