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Wils Stefan

Address : Theoretical Neurobiology
University of Antwerp
BIOMED, Campus CDE
Universiteitsplein 1
2610 Wilrijk
Belgium

Office : T5-38

Telephone : +32 3 820 2648

Email : stefanattnb.ua.ac.be


Research activity :

Many neural processes, such as learning and synaptic transmission, are thought to be mediated by chemical signaling pathways inside and in between nerve cells. My main aim in our lab is the development of simulation algorithms that can simulate the kinetics of these pathways. Since many of these reactions involve only small numbers of molecules, we describe them as discrete stochastic processes. In addition, our algorithms can take into account spatial distributions of molecules, diffusion and various boundary conditions such as plasma membranes and membrane-associated receptors and channels. I m also the author of a software implementation of these algorithms. This software is currently being developed for a study of various aspects of the plasticity induction pathways in the cerebellar parallel fiber-Purkinje cell synapses, but will eventually be released as a general computational tool for stochastic simulation of 3-dimensional reaction-diffusion systems in biology.

Papers :