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Robberechts Quinten

Address : Theoretical Neurobiology
University of Antwerp
BIOMED, Campus CDE
Universiteitsplein 1
2610 Wilrijk
Belgium

Office : T5-37

Telephone : +32 3 820 2610

Email : quintenattnb.ua.ac.be


Research activity :

My research focuses on the synaptic plasticity of the excitatory synaptic input of the parallel fibers in the molecular layer on the Golgi cell, the largest interneuron of the cerebellar cortex. Whether these synapses are actually plastic has as yet not been shown. The induction of long-term depression or long-term potentiation of these synapses must have far-reaching effects on the functioning of the cerebellar cortical network, not only considering the transmission of activity from the mossy fibers via the granule cells to the Purkinje cells, but also considering the reverse synaptic plasticity of the parallel fiber Purkinje cell synapse. An important additional aspect will be to study the effect of blocking or activating metabotropic glutamate receptors (mGluRs), and more specifically in the case of the Golgi cell the effect of mGluR2 on the synaptic plasticity of these synapses.

Papers :